Head-to-Head

Overview

Lorenzo Musetti and Stefanos Tsitsipas have met 7 times since 2021. Stefanos Tsitsipas leads 5–2. On clay, Stefanos Tsitsipas leads 4–2. Their first encounter was at the 2021 Acapulco (SF), won by Stefanos Tsitsipas. Most recently they met at the 2025 Madrid Masters (R32), with Lorenzo Musetti winning. Lorenzo Musetti has won the last 2 meetings.