Head-to-Head

Overview

Lorenzo Musetti and Reilly Opelka have met 4 times since 2021. Reilly Opelka leads 3–1. On hard, Reilly Opelka leads 2–1. Their first encounter was at the 2021 Rome Masters (R32), won by Reilly Opelka. Most recently they met at the 2024 Us Open (R128), with Lorenzo Musetti winning.